Stereotactic core biopsy breast and blood cell by-products: a source of material for molecular genetics research--initial experience.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 11230670.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Stereotactic core biopsy washings and blood drop samples, routinely discarded by-products, provide satisfactory fresh cellular material for flow cytometry and molecular genetics microsatellite polymerase chain reaction (PCR) analysis for detection of loss of DNA alleles (loss of heterozygosity). Cytokeratin-positive (epithelial) cells from the core biopsy washings were sorted by means of flow cytometry prior to PCR analysis. DNA allele loss was detected in benign breast epithelial cells in three (20%) of 15 patients.
Medical subject headings
- Biopsy
- Blood Cells
- Breast
- Breast Neoplasms
- Loss of Heterozygosity
- Polymerase Chain Reaction