Comparison of three rat strains for development of radiation-induced lung injury after hemithoracic irradiation.
other · Level V
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- Record sourced from PubMed, PMID 11230893.
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Abstract
The purpose of this study is to define differences in radiation sensitivity among rat strains using breathing frequency and lung perfusion as end points of radiation-induced lung injury. The results have confirmed previous findings in mice showing that under stringently controlled iso-dose/volume irradiation conditions, substantial differences can be found in susceptibility to functional lung damage after radiation.
Medical subject headings
- Disease Models, Animal
- Lung
- Lung Diseases
- Radiation Injuries
- Rats, Inbred Strains