Immune privilege or inflammation? Insights into the Fas ligand enigma.

O'Connell, J; Houston, A; Bennett, M W; O'Sullivan, G C; Shanahan, F · Nat Med · 2001

review · Level V

Where this comes from

Abstract

Fas ligand (FasL) has become an enigmatic molecule: some evidence indicates that it contributes to immune privilege in tissues and tumors, whereas other data demonstrates that FasL can elicit inflammation. New findings may begin to reconcile the paradoxical effects of FasL.

Medical subject headings