Ophthalmic drops causing coma in an infant.

Berlin, R J; Lee, U T; Samples, J R; Rich, L F; Tang-Liu, D D; Sing, K A; Steiner, R D · J Pediatr · 2001

case_report · Level V

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Abstract

A 1-month-old infant with Peters anomaly had recurrent episodes of unresponsiveness, hypotension, hypotonia, hypothermia, and bradycardia. An extensive medical evaluation determined these episodes to be caused by brimonidine, an anti-glaucoma agent. There is the potential for serious toxic effects from the systemic absorption of topically applied ophthalmic agents in children.

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