Immunoblotting detection of gamma-catenin (plakoglobin) antibody in the serum of a patient with paraneoplastic pemphigus.
case_report · Level V
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Abstract
We report a patient with paraneoplastic pemphigus associated with a thymic tumour. Immunoblot study using affinity-purified gamma-catenin protein revealed that his serum recognized gamma-catenin (plakoglobin) in epidermal, thymic tumour and mouse bladder extracts.
Medical subject headings
- Autoantibodies
- Cytoskeletal Proteins
- Paraneoplastic Syndromes
- Pemphigus