Intravenous amiodarone in intensive care. Time for a reappraisal?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 11271079.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Amiodarone is widely used in intensive care units for the treatment of a variety of arrhythmias. It is currently the drug of choice for supraventricular tachyarrhythmias in many units because of its combination of efficacy and safety. This review summarises the current state of knowledge regarding the short-term administration of intravenous amiodarone to control arrhythmias in perioperative, coronary care and intensive care patients. It outlines the electrophysiology, haemodynamics, pharmacokinetics and toxicity of the drug. In particular, it examines the recent concerns regarding acute pulmonary toxicity.
Medical subject headings
- Amiodarone
- Anti-Arrhythmia Agents
- Arrhythmias, Cardiac
- Critical Care