Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component.
case_report · Level V
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- Record sourced from PubMed, PMID 11271555.
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Abstract
We report a case of chordoma containing a spindle cell sarcomatoid component with a gradual transition from conventional chordoma. Immunohistochemically, many tumor cells in both conventional chordoma and sarcomatoid components were positive for cytokeratins (AE1/AE3, CAM5.2) and epithelial membrane antigen as well as vimentin. This report provides a rare example of sarcomatoid chordoma. Familiarity with this type of bone tumor should help to avoid confusion with dedifferentiated chordoma and other spindle cell sarcomas or carcinomas.
Medical subject headings
- Bone Neoplasms
- Chordoma
- Sacrum
- Sarcoma
Anatomy
- sacrum-coccyx