Infantile hypertrophic pyloric stenosis and asymptomatic joint hypermobility.

De Felice, C; Di Maggio, G; Toti, P; Parrini, S; Salzano, A; Lagrasta, U E; Bagnoli, F · J Pediatr · 2001

case_control · Level III

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Abstract

A significant association with asymptomatic joint hypermobility was observed in 37 children with a history of infantile hypertrophic pyloric stenosis (P =.0016) and their parents (mothers, P <.0001; fathers, P <.05). The subjects with articular hypermobility showed an increased frequency of absent mandibular frenulum, thereby suggesting the presence of a previously unrecognized, systemic abnormality of the extracellular matrix.

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