Linear IgA bullous dermatosis in a patient with renal cell carcinoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 11298552.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal bullous disease with heterogeneous clinical manifestations, characterized by linear deposition of IgA along the epidermal basement membrane zone. We report a patient with a metastasized renal cell carcinoma who developed an extensive blistering eruption. The lesions showed immunopathological findings characteristic of LABD. The patient showed a fair response to prednisolone and dapsone. Treatment to control the LABD was no longer required when interferon-alfa was started as palliative therapy for the metastasized renal cell carcinoma. The association of LABD and malignancies has been documented before and is not due to mere chance alone.
Medical subject headings
- Carcinoma, Renal Cell
- Immunoglobulin A
- Kidney Neoplasms
- Paraneoplastic Syndromes
- Skin Diseases, Vesiculobullous