The efficacy of Xialine in patients with xerostomia resulting from radiotherapy for head and neck cancer: a pilot-study.

Jellema, A P; Langendijk, H; Bergenhenegouwen, L; van der Reijden, W; Leemans, R; Smeele, L; Slotman, B J · Radiother Oncol · 2001

rct · Level II

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Abstract

Changes in subjective sensations due to xerostomia before and after administration of Xialine, a xanthan gum-based saliva substitute, were evaluated in 30 patients with radiation-induced xerostomia using the QLQ-H&N35. Xerostomia in general decreased with both Xialine and placebo to almost the same degree. A trend was seen for Xialine to improve problems with speech and senses.

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