Tissue engineering of vascular bypass grafts: role of endothelial cell extraction.
review · Level V
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Abstract
Surgical treatment of vascular disease has become common. The use of synthetic materials is limited to grafts larger than 5-6 mm, because of the frequency of occlusion observed with small-diameter prosthetics. An alternative would be a hybrid or tissue-engineered graft with the surface coated with a monolayer of the patients' own endothelial cells. This review examines the various techniques and technologies used to date in order to extract endothelial cells for such graft engineering.
Medical subject headings
- Biomedical Engineering
- Blood Vessel Prosthesis
- Cell Transplantation
- Endothelium