The leser-trelat sign in association with carcinoma of the ampulla of Vater.

Klimopoulos, S; Kounoudes, C; Pantelidaki, C; Skrepetou, K; Papoudos, M; Katsoulis, H · Am J Gastroenterol · 2001

case_report · Level V

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Abstract

A 45-yr-old woman was admitted to our hospital for surgical treatment of obstructive jaundice. She was treated by a standard pancreatoduodenectomy (Whipple procedure). The biopsy of the specimen disclosed an adenocarcinoma of the ampulla of Vater. Six months before the appearance of the obstructive jaundice, she noted a sudden onset of many seborrheic keratoses on the upper part of her trunk and upper extremities. This, to our knowledge, is the first case of Leser-Trelat sign associated with adenocarcinoma of the ampulla of Vater.

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