Cryoglobulinemia associated with Purtscher-like retinopathy.
case_report · Level V
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Abstract
To report a case of Purtscher-like retinopathy in a young man with chronic hepatitis C--associated cryoglobulinemia. Case report. A 44-year-old Caucasian man with chronic hepatitis C developed sudden loss of vision in the left eye and abdominal pain. Ocular fundus examination revealed peripapillary cotton-wool spots and superficial retinal whitening in the macula. Systemic evaluation revealed markedly elevated rheumatoid factor, hypertension, and acute renal insufficiency. A renal biopsy demonstrated intravascular deposition of immunoglobulins IgG and IgM and complement consistent with type II mixed cryoglobulinemia. Clinicians should consider cryoglobulinemia in the differential diagnosis of a patient with Purtscher-like retinopathy and history of infection with hepatitis C.
Medical subject headings
- Cryoglobulinemia
- Hepatitis C, Chronic
- Retinal Diseases