Construction of DNA restriction maps based on a simplified experiment.

Błazewicz, J; Formanowicz, P; Kasprzak, M; Jaroszewski, M; Markiewicz, W T · Bioinformatics · 2001

basic_science · Level V

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Abstract

A formulation of a new problem of the restriction map construction based on a simplified digestion experiment and a development of an algorithm for solving both ideal and noisy data cases of the introduced problem. A simplified partial digest problem and a branch and cut algorithm for finding the solution of the problem.

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