Therapeutic implications of inflammation in atherosclerotic cardiovascular disease.

Selzman, C H; Miller, S A; Harken, A H · Ann Thorac Surg · 2001

review · Level V

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Abstract

Atherosclerosis represents a spectrum of pathologic lesions with diverse clinical sequelae. In this review, we build upon the paradigm that arteriosclerosis represents an inflammatory disease. By examining mechanisms involved in the response to vascular injury, we can more effectively implement targeted therapy aimed at halting or regressing arteriosclerosis.

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