The effect on the hemodynamic stability of varying calcium chloride administration during protamine infusion in pediatric open-heart patients.
rct · Level II
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Abstract
We conducted a randomized study in 147 pediatric patients undergoing cardiopulmonary bypass to determine when there are any differences in hemodynamic effects if CaCl(2) 20 mg/kg and protamine 5mg/kg are mixed together and infused over 10 min versus administering half of the calcium dose (10 mg/kg) as a bolus followed by a 10-min infusion of protamine 5 mg/kg and CaCl(2) 10mg/kg.
Medical subject headings
- Calcium Chloride
- Cardiac Surgical Procedures
- Hemodynamics
- Heparin Antagonists
- Protamines