Feedback control of a biodynamical model of HIV-1.
basic_science · Level V
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- Record sourced from PubMed, PMID 11442287.
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Abstract
We describe a continuous differential equation model of the interaction dynamics of HIV-1 and CD4 and CD8 lymphocytes in the human body. We demonstrate several methods of stable control of the HIV-1 population using an external feedback control term that is analogous to the introduction of a therapeutic drug regimen. We also show how the immune system components can be bolstered against the virus through a feedback control approach.
Medical subject headings
- Acquired Immunodeficiency Syndrome
- Anti-HIV Agents
- CD4-CD8 Ratio
- HIV-1
- Nonlinear Dynamics