Role of Toll-like receptors in inflammatory response in macrophages.
review · Level V
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Abstract
The innate immune response is the first line of defense against infectious disease. It is vital that the host detect the pathogen and rapidly mount a defense. The Toll-like family of receptors have evolved to detect conserved patterns on pathogens. When stimulated, these receptors activate the inflammatory response.
Medical subject headings
- Bacterial Infections
- Drosophila Proteins
- Immunity, Innate
- Macrophage Activation
- Macrophages
- Membrane Glycoproteins
- Receptors, Cell Surface