Pemphigus foliaceus with prominent neutrophilic pustules.
case_report · Level V
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Abstract
We describe four patients with generalized scaly and pustular skin lesions showing extensive neutrophilic infiltration in the subcorneal region of the epidermis. Immunofluorescence, immunoblot and enzyme-linked immunosorbent assay analyses detected IgG antibodies reacting exclusively with desmoglein 1, the pemphigus foliaceus antigen. This study indicates that pemphigus foliaceus may show prominent neutrophilic pustular skin lesions.
Medical subject headings
- Neutrophil Infiltration
- Pemphigus
- Skin Diseases, Vesiculobullous