Efficacy of high dose steroid therapy in children with severe acute transverse myelitis.

Defresne, P; Meyer, L; Tardieu, M; Scalais, E; Nuttin, C; De Bont, B; Loftus, G; Landrieu, P et al. · J Neurol Neurosurg Psychiatry · 2001

retrospective_cohort · Level III

Where this comes from

Abstract

No effective treatment has been demonstrated for patients with acute transverse myelopathy. In a multicentre controlled study, 12 children with severe acute transverse myelopathy were treated with intravenous methylprednisolone (IVMP) and compared with a historical group of 17 patients. The treatment had a significant effect on the proportion of patients walking independently at 1 month and on the proportion with full recovery at 1 year, with no differences in the frequency of complications between the two groups.

Medical subject headings