Tularemia epidemic in northwestern Spain: clinical description and therapeutic response.

Pérez-Castrillón, J L; Bachiller-Luque, P; Martín-Luquero, M; Mena-Martín, F J; Herreros, V · Clin Infect Dis · 2001

case_series · Level IV

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Abstract

This study describes the clinical characteristics of tularemia in Spain's first epidemic outbreak and the therapeutic response and compares the efficacy of 3 antibiotics (streptomycin, ciprofloxacin, and doxycycline). For 142 cases of tularemia, the therapeutic failure rate was 22.5%; ciprofloxacin was the antibiotic with the lowest percentage of therapeutic failures and with the fewest side effects.

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