Discriminant analysis and its application in DNA sequence motif recognition.
review · Level V
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Abstract
Identification of functional motifs in a DNA sequence is fundamentally a statistical pattern recognition problem. Discriminant analysis is widely used for solving such problems. This paper will review two basic parametric methods: LDA (linear discriminant analysis) and QDA (quadratic discriminant analysis). Their usage in recognition of splice sites and exons in the human genome will be demonstrated.
Medical subject headings
- Computational Biology
- Discriminant Analysis
- Sequence Analysis, DNA