Hippocampal sclerosis following brief generalized seizures in adulthood.

Briellmann, R S; Newton, M R; Wellard, R M; Jackson, G D · Neurology · 2001

case_report · Level V

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Abstract

This report describes a patient who had a first generalized tonic clonic seizure (GTCS) at the age of 18 years. The initial MRI scan was normal on visual and quantitative examination. After a further six GTCS, a second MRI scan showed reduced hippocampal volume and increased hippocampal T2 signal, which was confirmed in a third scan. Therefore, hippocampal sclerosis may be acquired in adulthood after brief GTCS.

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