Lack of seroconversion in a health care worker after polymerase chain reaction-documented acute hepatitis C resulting from a needlestick injury.
case_report · Level V
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- Record sourced from PubMed, PMID 11477531.
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Abstract
We present a case of documented acute hepatitis C that occurred in a health care worker who sustained a needlestick injury while caring for an individual who was infected with both hepatitis C virus (HCV) and human immunodeficiency virus (HIV). According to the findings of third-generation serological assays performed during a follow-up of >1 year, the health care worker, who was treated with interferon-alpha (during weeks 2-6) and ribavirin (during weeks 5-9), did not develop antibodies against HCV, in spite of documentation of an HCV-specific T cell response.
Medical subject headings
- Hepacivirus
- Hepatitis C
- Hepatitis C Antibodies
- Infectious Disease Transmission, Patient-to-Professional
- Needlestick Injuries