Reversed end-diastolic flow in first-trimester umbilical artery: an ominous new sign for fetal outcome.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 11483929.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The purpose of this study was to assess the fetal outcome of first-trimester pregnancies with reversed end-diastolic flow in the umbilical artery. Doppler studies in the umbilical artery were carried out in 2970 consecutive pregnancies scanned at 10 to 14 weeks. We observed 11 (0.4%) cases of reversed end-diastolic flow. Of these, an autosomal trisomy was shown in 7 and a congenital heart defect in 2 additional fetuses. Fetal demise was observed in 5 pregnancies, neonatal death was observed in 1, and termination of pregnancy was carried out in 4. Only 1 fetus survived. Reversed end-diastolic flow in first-trimester umbilical artery signals an ominous prognosis even with normal karyotype.
Medical subject headings
- Diastole
- Fetal Diseases
- Pregnancy Outcome
- Umbilical Arteries
- Vascular Diseases