Prevalence and correlates of parkinsonism in patients with primary depression.

Starkstein, S E; Petracca, G; Chemerinski, E; Merello, M · Neurology · 2001

cross_sectional · Level IV

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Abstract

The authors examined the prevalence, clinical correlates, and longitudinal changes of parkinsonism in 94 patients with primary depression and 20 healthy control subjects. Parkinsonism was present in 20% of patients with primary depression. This syndrome was significantly associated with older age, more severe depression, and more severe cognitive impairment. In a subgroup of depressed patients, parkinsonism was reversible upon recovery from the mood disorder.

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