Response to cancer therapy in a patient with a paraneoplastic choreiform disorder.
case_report · Level V
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- Record sourced from PubMed, PMID 11524490.
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Abstract
The authors report a patient with chorea and multifocal neurologic abnormalities associated with a small-cell lung carcinoma. A previously unreported antibody directed at a 76-kD neuronal protein antigen was identified in both serum and CSF. Antitumor treatment resulted in dramatic and sustained clinical neurologic and serologic responses.
Medical subject headings
- Carcinoma, Small Cell
- Chorea
- Lung Neoplasms
- Paraneoplastic Syndromes