Dopaminergic therapy with carbidopa L-dopa for left neglect after stroke: a case series.

Mukand, J A; Guilmette, T J; Allen, D G; Brown, L K; Brown, S L; Tober, K L; Vandyck, W R · Arch Phys Med Rehabil · 2001

case_series · Level IV

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Abstract

To evaluate the efficacy of carbidopa L-dopa (Sinemet) in reducing left spatial neglect after stroke. Case series. Inpatient neurorehabilitation unit in a regional rehabilitation center. A convenience sample of 4 women with right brain strokes and left neglect. A trial of carbidopa L-dopa to treat left neglect, if indicated by selected subtests of the Behavioral Inattention Test (BIT). Baseline and posttreatment evaluation with the modified BIT and the FIM instrument. Three of 4 subjects had significant improvements in their modified BIT scores (8%, 12%, 27%, respectively) and their functional status on the FIM. With further study, carbidopa L-dopa may be shown to reduce unilateral spatial neglect and thereby improve rehabilitation outcomes.

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