A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma.

Tsai, Y G; Lee, M Y; Yang, K D; Chu, D M; Yuh, Y S; Hung, C H · J Pediatr · 2001

rct · Level II

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Abstract

This study was conducted to investigate whether a single dose of nebulized budesonide effectively decreased airway inflammation as demonstrated by exhaled nitric oxide (eNO) levels. A single dose of nebulized budesonide, but not nebulized terbutaline, rapidly decreased eNO levels in 6 hours. The decrease in eNO levels induced by nebulized budesonide was correlated to an increase in peak expiratory flow rate.

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