Satellite potentials on EMG: neurophysiologic evidence of axonal transection in MS?
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 11571352.
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Abstract
To detect signs of axonal damage in MS, the authors investigated the occurrence in EMG of motor unit action potentials with satellite potentials (SP-MUAP) in the upper limb muscles in 10 consecutive patients with MS with cervical spinal cord demyelinating lesions and 10 control subjects. Subjects' SP-MUAP rate was 0 to 2.5% (median 0%) in the control group, and 0 to 17.5% (median 7.5%) in the MS group (p < 0.01). Motor unit remodeling secondary to axonal transection of spinal motor neurons traversing cervical demyelinating lesions may be hypothesized.
Medical subject headings
- Axons
- Electromyography
- Multiple Sclerosis