Switching and signaling at the telomere.
review · Level V
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- Record sourced from PubMed, PMID 11572773.
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Abstract
This review describes the structure of telomeres, the protective DNA-protein complexes at eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere functions. Also discussed are cellular responses to compromising the functions of telomeres and of telomerase, which synthesizes telomeric DNA.
Medical subject headings
- Telomerase
- Telomere