The long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance.
case_report · Level V
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Abstract
Our report describes for the first time the continuous long-term intrathecal application of S(+)-ketamine in a patient with chronic pain and morphine tolerance. Intrathecally applied S(+)-ketamine led to a significant pain reduction and consecutively reduced the doses of intrathecal morphine required for pain relief even several weeks after the cessation of the 24-day period of intrathecal S(+)-ketamine administration.
Medical subject headings
- Analgesics
- Analgesics, Opioid
- Anesthetics, Dissociative
- Ketamine
- Morphine
- Pain