Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody.
case_series · Level IV
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- Record sourced from PubMed, PMID 11591857.
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Abstract
The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.
Medical subject headings
- Ataxia
- Gangliosides
- Immunoglobulin G