SP-RING for SUMO: new functions bloom for a ubiquitin-like protein.
review · Level V
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Abstract
SUMO is covalently linked to a variety of cellular proteins. Three groups now describe related E3-like factors that enhance transfer of SUMO to specific proteins. This family of factors includes proteins important for chromosome condensation, signal transduction, and ion channel biogenesis.
Medical subject headings
- Ligases
- Protein Processing, Post-Translational
- SUMO-1 Protein
- Saccharomyces cerevisiae Proteins
- Ubiquitin-Protein Ligases