Error-prone DNA polymerases: novel structures and the benefits of infidelity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 11595180.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.
Medical subject headings
- DNA-Directed DNA Polymerase