Two episodes of leukoencephalitis associated with recombinant hepatitis B vaccination in a single patient.

Konstantinou, D; Paschalis, C; Maraziotis, T; Dimopoulos, P; Bassaris, H; Skoutelis, A · Clin Infect Dis · 2001

case_report · Level V

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Abstract

Cases of central nervous system demyelination have been reported after recombinant hepatitis B vaccination, but no causal link has been clearly demonstrated. We present the first case report involving the occurrence of 2 episodes of leukoencephalitis in a previously healthy patient after vaccination and rechallenge with hepatitis B vaccine.

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