Interaction of isotretinoin with endogenous retinoids.
review · Level V
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Abstract
Isotretinoin exhibits antiproliferative and antiandrogenic effects on the sebaceous glands by yet unknown mechanisms. This review focuses on a putative mechanism of action of isotretinoin involving the interaction of isotretinoin with the metabolism of endogenous retinoids and androgens.
Medical subject headings
- Androgens
- Dermatologic Agents
- Isotretinoin
- Retinoids
- Sebaceous Glands