G protein signaling and asymmetric cell division.
basic_science · Level V
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- Record sourced from PubMed, PMID 11672519.
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Abstract
Asymmetric cell division depends on the polarization of the dividing cell for the correct alignment of the mitotic spindle and the localization of cytoplasmic determinants. Receptor-independent activation of heterotrimeric G proteins by the Drosophila GoLoco protein Partner of Inscuteable seems to represent a novel mechanism to control these events.
Medical subject headings
- Cell Cycle Proteins
- Cell Division
- Drosophila Proteins
- GTP-Binding Proteins