Systemic tizanidine hydrochloride (Zanaflex) partially decreases experimental postoperative pain in rats.

Hord, A H; Denson, D D; Azevedo, M I · Anesth Analg · 2001

basic_science · Level V

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Abstract

Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain.

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