Profound T-lymphocytopenia and cryptococcemia in a human immunodeficiency virus-seronegative patient with disseminated tuberculosis.
case_report · Level V
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Abstract
A 47-year-old human immunodeficiency virus-seronegative West African man who presented in extremis with cachexia, lymphadenopathy, multiple organ dysfunction, and marked T-lymphocytopenia received the diagnosis of disseminated tuberculosis, cryptococcal pneumonia, and cryptococcemia. His subsequent course and our review of the literature suggest that the profound T-lymphocytopenia and ensuing cryptococcal disease were likely attributable to disseminated tuberculosis.
Medical subject headings
- Cryptococcosis
- HIV Seronegativity
- Opportunistic Infections
- T-Lymphocytopenia, Idiopathic CD4-Positive
- Tuberculosis, Pulmonary