Antifungal activity against Candida species of the selective serotonin-reuptake inhibitor, sertraline.

Lass-Flörl, C; Dierich, M P; Fuchs, D; Semenitz, E; Ledochowski, M · Clin Infect Dis · 2001

case_report · Level V

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Abstract

Three patients with premenstrual dysphoric disorder (PMDD) and recurrent vulvovaginal candidiasis (VVC) underwent sertraline therapy (Tresleen, a selective serotonin-reuptake inhibitor; Pfizer) for PMDD. During sertraline intervention, patients had no recurrent episodes of acute VVC. Antifungal activity was observed for sertraline against various isolates of Candida species.

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