Rapid infusion of intravenous immune globulin in patients with neuromuscular disorders.

Grillo, J A; Gorson, K C; Ropper, A H; Lewis, J; Weinstein, R · Neurology · 2001

retrospective_cohort · Level III

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Abstract

The safety and efficiency of a novel method of rapid-infusion IV immunoglobulin (IVIg) were retrospectively reviewed in 50 patients with neuromuscular disorders. There were 89 adverse events after 341 rapid infusions (26%), 3.5% of which were considered to be major (requiring hospitalization) and 66% minor. All patients recovered without sequelae, and there were no deaths. Fourteen of 17 patients (82%) receiving maintenance therapy preferred rapid IVIg infusion because of its convenience. Rapid-infusion IVIg can be given safely and conveniently in many patients with neuromuscular disorders.

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