Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).

Ravenscroft, J; Goulden, V; Wilkinson, M · J Am Acad Dermatol · 2001

case_report · Level V

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Abstract

Photochemotherapy with psoralens and UVA (PUVA) is widely used in the treatment of psoriasis and many other skin conditions. Cutaneous adverse reactions to 8-methoxypsoralen (8-MOP) appear to be rare and may be difficult to distinguish from phototoxicity or UV-induced polymorphic light eruption. We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis.

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