Late opacification of the foldable hydrophilic acrylic lens SC60B-OUV.

Frohn, A; Dick, H B; Augustin, A J; Grus, F H · Ophthalmology · 2001

case_series · Level IV

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Abstract

To investigate the cause of severe central opacification in 41 foldable acrylic intraocular lenses (IOLs) requiring explantation. Another IOL was opacified in the original sealed vial. Case series and laboratory analysis. Light microscopy, high performance liquid chromatography, sodium dodecyl sulfate polyacoylamide gel electrophoresis, spectrometric analysis, and autoclaving. Neither fatty acids nor proteins could be identified within the IOLs. Spectrometric analysis yielded absorption peaks in the ultraviolet spectral range. The spectroscopic findings indicate premature aging of the ultraviolet blocking agent. The source of the opacification is a change in the IOL material itself.

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