Onset of multiple sclerosis associated with anti-TNF therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 11723281.
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Abstract
Therapies aimed at inhibiting tumor necrosis factor (TNF), a proinflammatory cytokine implicated in autoimmune disease are effective, especially for rheumatoid arthritis. We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis. It is possible that the inhibition of TNF triggered MS in this individual.
Medical subject headings
- Antirheumatic Agents
- Arthritis, Juvenile
- Immunoglobulin G
- Multiple Sclerosis
- Receptors, Tumor Necrosis Factor
- Tumor Necrosis Factor-alpha