Motor perseveration is an early sign of Parkinson's disease.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 11739836.
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Abstract
Perseveration in the generation of random motor behavior was examined by means of the Vienna perseverance task in groups of de novo (n = 18) and treated (n = 18) patients with early PD, and in control subjects (n = 18). In comparison with control subjects, both the de novo and treated patients with PD were relatively unable to generate random motor sequences, indicating a decreased ability to switch cortical behavioral programs in PD. An impairment of random motor generation appears to be a very early feature of PD.
Medical subject headings
- Antiparkinson Agents
- Parkinson Disease
- Psychomotor Performance
- Serial Learning
- Stereotyped Behavior