Takayasu arteritis and atherosclerosis: illustrating the consequences of endothelial damage.
case_report · Level V
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Abstract
The excess of cardiovascular morbidity associated with chronic vasculitic disease has become a focus of considerable research, particularly regarding the link between endothelial damage and the development of atherosclerosis. We describe a case of Takayasu arteritis treated sub-optimally by today's standards, giving rise to an 11 year history of progressive, stepwise decline associated with cerebrovascular events and leading to early death. Postmortem findings presented a picture of chronic atherosclerotic disease but in a distribution consistent with lesions of Takayasu arteritis.
Medical subject headings
- Arteriosclerosis
- Endothelium, Vascular
- Takayasu Arteritis