Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on transitional naive T cells (CD4(+)CD45RA(+)CD29(+)).
rct · Level II
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Abstract
Changes in immunologic status were evaluated in 25 HIV-infected men randomly assigned to a 10-week stress management intervention or a wait-list control condition. The authors monitored changes in number of transitional naive T cells (CD4(+)CD45RA(+)CD29(+)) over 6-12 months after the completion of the intervention. Men receiving stress management had higher CD4(+) CD45RA(+)CD29(+) cell counts at follow-up than did the control subjects. This difference was independent of initial number of naive T cells and HIV virus load. Stress management is associated with immunologic reconstitution in HIV-positive gay men.
Medical subject headings
- CD4-Positive T-Lymphocytes
- Cognitive Behavioral Therapy
- HIV Infections
- Homosexuality, Male
- Integrin beta1
- Leukocyte Common Antigens
- Stress, Psychological
- T-Lymphocyte Subsets