Squamous cell carcinoma arising in the skin of a deltopectoral flap 27 years after pharyngeal reconstruction.
case_report · Level V
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- Record sourced from PubMed, PMID 11774408.
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Abstract
Development of a second primary squamous cell carcinoma in the skin of a flap used for pharyngeal reconstruction is rare. A case of squamous cell carcinoma is presented arising in a deltopectoral flap used to reconstruct the hypopharynx 27 years after total laryngectomy. Three previous reports found on review of the literature are summarized. A second primary squamous cell carcinoma may arise in the skin of a myocutaneous flap in the absence of any obvious risk factors. We suspect that long-term exposure of the skin of the flap lining the pharynx to saliva may have been a significant factor in the development of this malignancy. Long-term follow up and awareness of this complication is required for patients with soft tissue reconstruction of the oral cavity and pharynx.
Medical subject headings
- Carcinoma in Situ
- Carcinoma, Squamous Cell
- Neoplasms, Second Primary
- Pharyngeal Neoplasms
- Surgical Flaps