Human recombinant activated protein C in meningococcal sepsis.
case_report · Level V
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Abstract
A 19-year-old woman presented with purpura fulminans and septic shock; subsequently, progressive coagulopathy, widespread purpura fulminans associated with meningococcemia, severe shock, respiratory, and renal failure developed. This clinical course was associated with depletion of functional protein C levels to < 5%. We describe her clinical course and therapy with human recombinant activated protein C.
Medical subject headings
- Protein C
- Protein C Deficiency
- Waterhouse-Friderichsen Syndrome